Syntheses of bifunctionalized phosphine complexes via ruthenium promoted stepwise hydrophosphination, insertion, hydration, and hydroamination reactions.
Date of Issue2010
School of Physical and Mathematical Sciences
This thesis describes the asymmetric syntheses of bifunctionalized phosphine complexes, which contain a stereogenic center at phosphorus, through various reactions, including insertion, hydrophosphination, hydration, and hydroamination. Promoted by the coordination of diprop-1-ynylphenylphosphine to ruthenium, the two alkyne moieties thereafter were functionalized by different reactions, which thus led to the formation of a chiral phosphorous center. This strategy presented is valuable and can be widely used in the synthesis of chiral phosphines.
DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds