Development of new synthetic methodologies and their application towards synthesis of natural products.
Date of Issue2010
School of Physical and Mathematical Sciences
The thesis consists of four parts: 1. Development of methodology namely indium (III) chloride catalyzed Mukaiyama-Michael addition for the construction of 2,6-anti pyran 2. Application of indium (III) chloride catalyzed Mukaiyama-Michael addition in the total synthesis of polyrachitide A 3. Application of indium (III) chloride catalyzed Mukaiyama-Michael addition in the total synthesis of apicularen A 4. Synthetic studies towards marinomycins, a potential antitumor-antibiotic macrolide isolated from the marine sponges.
DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis