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Title: Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA
Authors: Luo, Ji
Keywords: DRNTU::Science::Chemistry::Biochemistry
Issue Date: 2010
Abstract: Some sequences of DNA that possess certain guanine or cytosine-riched stretches are capable of associating into two types of four-stranded DNA structures, namely G-quadruplex and i-motif respectively, which could exist in some biologically important regions of DNA such as the end of chromosomes and the regulatory regions of oncogenes. With the aim of exploring new properties and applications of quadruplex DNA during my graduate studies, we have investigated the factors that affect the G-quadruplex that could undergo self-cleavage reactions, and developed certain fluorescence-tagged circular i-motifs to be used as molecular probes.
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Theses

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