dc.contributor.authorWang, Yifeng
dc.date.accessioned2011-01-28T01:30:09Z
dc.date.accessioned2017-07-23T08:43:19Z
dc.date.available2011-01-28T01:30:09Z
dc.date.available2017-07-23T08:43:19Z
dc.date.copyright2011en_US
dc.date.issued2011
dc.identifier.citationWang, Y. F. (2011). Manganese(III)-mediated reactions of vinyl azides and 1,3-dicarbonyl compounds or cyclopropanols : synthesis of azaheterocycles. Doctoral thesis, Nanyang Technological University, Singapore.
dc.identifier.urihttp://hdl.handle.net/10356/42871
dc.description.abstractIn this thesis, the author describes efficient methods to synthesize azaheterocycles by using readily accessible vinyl azides as fundamental substrates. These methods involve iminyl radicals as key intermediates, which are generated by the addition of α- or β-carbonyl radicals to the C═C bond of vinyl azides with the elimination of dinitrogen. The α- and β-carbonyl radicals are generated by the oxidation of 1,3-dicarbonyl compounds and cyclopropanols with Mn(III) complexes, respectively. The construction of azaheterocyclic frameworks is achieved by the cyclization of iminyl radicals onto an intramolecular carbonyl group. Importantly, the radical chain reactions are then terminated by the reduction of alkoxy radicals by the resulting Mn(II) species to afford Mn(III)alkoxides, from which azaheterocyclic products are formed with regeneration of active Mn(III) species. Therefore, this characteristic oxidative initiation and reductive termination process promotes these reactions in a catalytic manner.en_US
dc.format.extent280 p.en_US
dc.language.isoenen_US
dc.subjectDRNTU::Science::Chemistry::Organic chemistry::Organic synthesisen_US
dc.titleManganese(III)-mediated reactions of vinyl azides and 1,3-dicarbonyl compounds or cyclopropanols : synthesis of azaheterocyclesen_US
dc.typeThesis
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.contributor.supervisorChiba Shunsukeen_US
dc.contributor.supervisorKoichi Narasakaen_US
dc.description.degreeDOCTOR OF PHILOSOPHY (SPMS)en_US


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