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Title: Development of drug loaded biodegradable polymer composite microparticles
Authors: Li, Yan
Keywords: DRNTU::Engineering::Chemical engineering::Biotechnology
Issue Date: 2011
Source: Li, Y. (2011). Development of drug loaded biodegradable polymer composite microparticles. Doctoral thesis, Nanyang Technological University, Singapore.
Abstract: Calcium hydroxyapatite (HA) is the main inorganic component of natural bones and widely used as coating material on bone implants due to its osteoconductive characteristic. Other metal ions besides Ca can be introduced into HA through ion exchange or coprecipitation method to form metal ion doped HA (MHA), which has been used as catalyst or absorbent. In this investigation, gadolinium(III) (Gd3+), neodymium(III) (Nd3+), manganese(II) (Mn2+) and iron(III) (Fe3+) substituted HA at different molar ratios (Madded/Caadded = XM, 0.01, 0.05, 0.1 and 0.2) were synthesized using wet chemical method coupled with ion exchange mechanism. Calcium hydroxide Ca(OH)2 and phosphoric acid H3PO4 were used as reactants.
DOI: 10.32657/10356/43712
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Theses

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