Influence of surface characteristic on endothelialization

Abstract

Nowadays lactic and glycolic acid polymers and their copolymers have been evaluated as a promising candidate material for cardiovascular stents since degradation products of lactic and glycolic acid polymers and their copolymers by hydrolysis are nontoxic in physiological environment, and the copolymers are able to offering a broad range of mechanical and degradation properties by varying their molecular weights and copolymerization ratios. However this application in blood-contacting devices is limited by its low speed of endothelialization. Therefore surface modification of polymer surface is investigated. The author researches on the influence of surface characteristics on the endothelialization. Otherwise the influence of incubation time on endothelialization is also investigated.