Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/45161
Title: | Coated magnetic carrier particles for targeted drug delivery | Authors: | Sibnath Kayal | Keywords: | DRNTU::Engineering::Materials::Biomaterials | Issue Date: | 2011 | Source: | Sibnath Kayal. (2011). Coated magnetic carrier particles for targeted drug delivery. Doctoral thesis, Nanyang Technological University, Singapore. | Abstract: | Magnetic drug targeting, using coated magnetic carrier particles (MCP), is an efficient method to localize drugs at the tumor site. In magnetically targeted drug delivery, MCP loaded with anti-cancer drugs are injected into the patient and an external magnetic field is used to concentrate MCP at the tumor site. Advantages include reduction in the drug dose and minimization of systemic side effects. The objective of this work is the synthesis, characterization and property evaluation of coated MCP, and experimental and modelling studies of the efficacy with which such particles can be captured by an external magnetic field. Gold coated iron (Fe@Au) and polyvinylalcohol coated iron oxide (PVA-IO) nanoparticles were synthesized and characterized by XRD, TEM, DLS, TGA, XPS, FTIR and VSM techniques. | URI: | https://hdl.handle.net/10356/45161 | DOI: | 10.32657/10356/45161 | Schools: | School of Materials Science & Engineering | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | MSE Theses |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
TmseG0500319C.pdf | 9.18 MB | Adobe PDF | View/Open |
Page view(s) 10
807
Updated on Mar 27, 2024
Download(s) 10
432
Updated on Mar 27, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.