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Title: Bio-based biodegradable scaffolds for tissue engineering applications : effect of fabrication method and cross-linker concentration on scaffold properties
Authors: Xue, Bin.
Keywords: DRNTU::Engineering::Materials::Biomaterials
Issue Date: 2011
Abstract: With increasing demand of engineered tissues, natural polymers are promising alternative to conventional synthetic scaffolding materials in terms of biocompatibility and overall interactions with cells. An example of a natural polymer is ovalbumin (OVA), which has yet to be intensively researched to evaluate its potential for tissue engineering applications. In this project, the effect of fabrication method and cross-linker concentration on ovalbumin scaffold properties was investigated. Glutaraldehyde (GA) was used to cross-link OVA; and two fabrication techniques, salt-leaching and freeze-drying, were used to fabricate OVA scaffolds. In addition, purification of OVA from chicken egg white was performed to investigate the feasibility of separating OVA from a simple ultrafiltration scheme.
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:MSE Student Reports (FYP/IA/PA/PI)

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