Effect of disinfectant solutions on pseudomonas aeruginosa

Abstract

Pseudomonas aeruginosa is one of the most common pathogens that can cause opportunistic infection in immunocompromised patients. It is one of the most common pathogens that can cause respiratory problems in infected patients, cystic fibrosis and other hospital acquired infections. Cancer patients and burn patients can suffer more serious signs and symptoms than other individuals. It is also the leading cause of nosocomial infections and hospital acquired pneumonia in intensive care unit (ICU). It can be spread by health care workers, staff, cleaners and medical equipments. Moreover, it becomes the major problem in health care because of its characteristics of developing resistance to antibiotics and forming biofilms. This report is to carry out the minimal inhibitory concentration of common floor cleaners against Pseudomonas aeruginosa (PAOl) and determine the resistance of PAOl with floor cleaners. In this study, four common floor cleaners were chosen for minimal inhibitory concentration and five floor cleaners were chosen to test the formation of resistance of PAOl. The time killing methods were analyzed. Phenol coefficient test was carried out as standard to compare with other floor cleaners. In this study, resistance was formed in two floor cleaners beyond 1 MIC and resistance was formed in 1 MIC in the other three solutions. Therefore, Pseudomonas aeruginosa (PAOl) can form resistance easily with the floor cleaners.