Experimental investigation on combination of ofloxacin and antimicrobial plant extracts (ethyl gallate and protocatechin)

Abstract

The uses of naturally-derived products for primary health care have steadily increased worldwide in recent years. Researchers have intensified their efforts in the area of exploring newer effective antimicrobial compounds due to the emergence of more powerful mutated strains of bacteria and it significantly becomes the leading health concern globally nowadays. With the current trend on increasing awareness in natural substances for medicine, plant-derived agents have been attracting much interest as natural alternatives comparing to synthetic compounds for the fact that microbes slowly develop resistance against antibiotics. Therefore, exploring plant products which have antimicrobial properties become fast-growing commercial exploitation of pharmaceutical industries.