Deposition and characterization of MgxFHA coatings and the osteoblastic cell response on their surfaces

Abstract

The performance of pure Hydroxyapatite (HA) coated titanium alloys used as a hard tissue implant material is not satisfactory due to insufficient short-term osseointegration and long-term stability issues. Previous studies concluded that the cation incorporation of magnesium (Mg) into HA gives rise to better osseointegration amongst other improved biological performances, while the anion incorporation of fluorine (F) into HA improves the long term stability in terms of better dissolution resistance and adhesion strength on Ti-alloy implants. Therefore, by incorporating both the cation and anion into HA, it is hoped to unite and enhance both short term as well as long term performances of the implant.