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Title: Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
Authors: Han Tun Aung
Keywords: DRNTU::Engineering
Issue Date: 2009
Publisher: Popular Science
Abstract: In this research work, a novel controlled drug delivery system was studied. The system is made up of water insoluble, biodegradable polymers; poly (D,L lactide) (PDLLA) and poly (D,L-lactide-co-glycolide) (PLGA), dissolved in N-methyl-2-pyrrolidone (NMP). Such a polymer solution forms gel depot upon injection into the body fluids and the depot itself gradually degrades with time. A highly potent drug, 5-fluorouracil (5-FU) is incorporated into the depot to achieve the sustainable release profile.
Description: 79 p.
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:MAE Theses

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