Dedifferentiation of hematopoietic stem cells into induced pluripotent stem cells

Abstract

In 2006,"iPS cells" were introduced for the first time in the field of biology by a group of scientists at Kyoto University led by Shinya Yamanaka. iPS cells which stands for induced pluripotent stem cells has opened a new horizon for researchers in stem cell and related areas especially in cell transplantation therapies. Since then many groups all over the world have started to explore this field and have used different strategies to improve the methods of generating iPS cells.