Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/47446
Title: Regulation of the actin cytoskeleton by the POPX2 phosphatase.
Authors: Xie, Yi.
Keywords: DRNTU::Science::Biological sciences
Issue Date: 2009
Source: Xie, Y. (2009). Regulation of the actin cytoskeleton by the POPX2 phosphatase. Doctoral thesis, Nanyang Technological University, Singapore.
Abstract: The actin cytoskeleton is crucial in maintaining cell morphology and mediating cell motility in eukaryotic cells. The organization of the actin architecture is regulated by a number of actin binding proteins and signaling molecules. Among them, the Rho family of small GTPases and their effector proteins play important roles in modulating the actin cytoskeleton. More than twenty members of the RHO proteins have been reported but RhoA, CDC42 and RAC1 remain the most well studied. Many of the Rho effector proteins are kinases. Hence the balance of phosphorylation activities is also implicated in the maintenance of the actin structures.
Description: 156 p.
URI: http://hdl.handle.net/10356/47446
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SBS Theses

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