Novel insights into the biological function of the high molecular weight PY235 rhoptry protein of plasmodium Yoelii
Jeya Kumar Ramalingam
Date of Issue2010
School of Biological Sciences
Malaria is one of the most economically important parasitic diseases in the world and is caused by Plasmodium species. The disease symptoms are due to the parasite's nature of invading and developing within the host erythrocyte. Invasion of malaria parasite in a suitable host cell involves a cascade of receptor-ligand interactions. Rodent malaria Py235 and their homologues in human Plasmodium falciparum play an important role in invasion. However, little is known about the biological function of these proteins except that they bind to erythrocytes.
Nanyang Technological University