Cell adhesion behavior on molecularly engineered surfaces.
Date of Issue2010
School of Chemical and Biomedical Engineering
Effective attachment of cells on biomaterials is one important requirement in designing engineered tissue substitute in application of tissue engineering. Engineering biomaterials surface with biomolecules including ECM proteins is a widely-used method to enhance cell adhesion. The advancement in tissue engineering requires the design of optimized biomaterial surface to facilitate tissue regeneration, which relies on a better understanding of cell adhesion behavior on engineered biomaterial surfaces. In this work, poly(lactic acid) (PLA) and carbon nanotubes (CNT), chosen as the representative of conventional biomaterials and novel nano-biomaterials, respectively, were surface-modified with ECM proteins, collagen type I (COL) and fibronectin (FN), to improve their compatibility.
Cell adhesion behavior
Nanyang Technological University