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https://hdl.handle.net/10356/47519
Title: | Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates | Authors: | Krisada Kittigowittana | Keywords: | DRNTU::Science::Biological sciences | Issue Date: | 2010 | Source: | Krisada Kittigowittana. (2010). Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates. Doctoral thesis, Nanyang Technological University, Singapore. | Abstract: | Contrast agents with high relaxivity are needed for increasing the sensitivity of magnetic resonance imaging (MRI) for novel clinical and research applications. Therefore, we are developing a new class of oligomer-based contrast agents by incorporating multiple-gadolinium complexes into peptides of controlled length and structure. This allows synthesis of a library of Gd-peptides with different sequences, peptide length and number of Gd-chelates. Screening this library will enable selection of oligomers with desired properties. | Description: | 190 p. | URI: | https://hdl.handle.net/10356/47519 | DOI: | 10.32657/10356/47519 | Schools: | School of Physical and Mathematical Sciences | Rights: | Nanyang Technological University | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SPMS Theses |
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SPMS_THESES_9.pdf | 19.37 MB | Adobe PDF | View/Open |
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