Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/47519
Title: Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
Authors: Krisada Kittigowittana
Keywords: DRNTU::Science::Biological sciences
Issue Date: 2010
Source: Krisada Kittigowittana. (2010). Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates. Doctoral thesis, Nanyang Technological University, Singapore.
Abstract: Contrast agents with high relaxivity are needed for increasing the sensitivity of magnetic resonance imaging (MRI) for novel clinical and research applications. Therefore, we are developing a new class of oligomer-based contrast agents by incorporating multiple-gadolinium complexes into peptides of controlled length and structure. This allows synthesis of a library of Gd-peptides with different sequences, peptide length and number of Gd-chelates. Screening this library will enable selection of oligomers with desired properties.
Description: 190 p.
URI: https://hdl.handle.net/10356/47519
DOI: 10.32657/10356/47519
Schools: School of Physical and Mathematical Sciences 
Rights: Nanyang Technological University
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Theses

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