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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hu, Xuhong | en |
dc.date.accessioned | 2012-01-09T07:52:19Z | en |
dc.date.available | 2012-01-09T07:52:19Z | en |
dc.date.copyright | 2011 | en |
dc.date.issued | 2011 | en |
dc.identifier.citation | Hu, X. H. (2011). Construction of 2,6-trans pyrans via Prins cyclization and its application towards the total synthesis of methyl sarcophytoate. Doctoral thesis, Nanyang Technological University, Singapore. | en |
dc.identifier.uri | https://hdl.handle.net/10356/47588 | en |
dc.description.abstract | Prins cyclization reaction involving a homoallylic alcohol with aldehyde is one of the most efficient methods to synthesize tetrahydropyran rings. However, due to the strong 1,3-diaxial interaction, the 2,6-cis tetrahydropyran moiety was formed preferably in most cases. The emphasis of this thesis is focused on the evolution of a convenient catalytic Prins cyclization for the construction of 2,6-trans pyranyl motifs and its application towards the total synthesis of natural product. | en |
dc.format.extent | 159 p. | en |
dc.language.iso | en | en |
dc.subject | DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis | en |
dc.title | Construction of 2,6-trans pyrans via Prins cyclization and its application towards the total synthesis of methyl sarcophytoate | en |
dc.type | Thesis | en |
dc.contributor.supervisor | Yang Hua Zheng | en |
dc.contributor.supervisor | Loh Teck Peng | en |
dc.contributor.school | School of Physical and Mathematical Sciences | en |
dc.description.degree | DOCTOR OF PHILOSOPHY (SPMS) | en |
dc.identifier.doi | 10.32657/10356/47588 | en |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
Appears in Collections: | SPMS Theses |
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TspmsG0702498A.pdf | 6.46 MB | Adobe PDF | ![]() View/Open |
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