dc.contributor.authorHu, Xuhong
dc.date.accessioned2012-01-09T07:52:19Z
dc.date.accessioned2017-07-23T08:43:30Z
dc.date.available2012-01-09T07:52:19Z
dc.date.available2017-07-23T08:43:30Z
dc.date.copyright2011en_US
dc.date.issued2011
dc.identifier.citationHu, X. H. (2011). Construction of 2,6-trans pyrans via Prins cyclization and its application towards the total synthesis of methyl sarcophytoate. Doctoral thesis, Nanyang Technological University, Singapore.
dc.identifier.urihttp://hdl.handle.net/10356/47588
dc.description.abstractPrins cyclization reaction involving a homoallylic alcohol with aldehyde is one of the most efficient methods to synthesize tetrahydropyran rings. However, due to the strong 1,3-diaxial interaction, the 2,6-cis tetrahydropyran moiety was formed preferably in most cases. The emphasis of this thesis is focused on the evolution of a convenient catalytic Prins cyclization for the construction of 2,6-trans pyranyl motifs and its application towards the total synthesis of natural product.en_US
dc.format.extent159 p.en_US
dc.language.isoenen_US
dc.subjectDRNTU::Science::Chemistry::Organic chemistry::Organic synthesisen_US
dc.titleConstruction of 2,6-trans pyrans via Prins cyclization and its application towards the total synthesis of methyl sarcophytoateen_US
dc.typeThesis
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.contributor.supervisorYang Hua Zheng
dc.contributor.supervisorLoh Teck Pengen_US
dc.description.degreeDOCTOR OF PHILOSOPHY (SPMS)en_US


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