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|Title:||Surface enhanced Raman-scattering protein sensor||Authors:||Loh, Wai Kit.||Keywords:||DRNTU::Engineering::Electrical and electronic engineering::Nanoelectronics||Issue Date:||2012||Abstract:||Raman spectroscopy is used to study vibrational modes in molecules. Depending on the constituent atomic masses and the molecular-bond strengths, each molecule possesses a unique set of vibrational frequencies, which allows it to be identified even from a complex background consisting of different other molecular species. In Surface Enhanced Raman Spectroscopy (SERS), unique optical property of metallic (example like Gold (Au) or Silver (Ag)) nano-structures are utilized to generate strong light fields localized near nano-protrusions or nano-crevices on the surface. An analyte placed or absorbed within these “hot-spot” areas would experience a strong excitation, resulting in an amplification of the Raman emission. One can thus use SERS hot-spots as an ultrasensitive sensing element for detecting specific molecules in a complex mixture. The project will investigate the use of SERS for protein sensing in bio-fluids with our collaborators in the Singapore Bio-imaging Consortium.||URI:||http://hdl.handle.net/10356/49789||Rights:||Nanyang Technological University||Fulltext Permission:||restricted||Fulltext Availability:||With Fulltext|
|Appears in Collections:||EEE Student Reports (FYP/IA/PA/PI)|
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