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Title: Material characterization of ca-alginate hydrogel
Authors: Nabilah Mashhur Ali
Keywords: DRNTU::Engineering::Bioengineering
DRNTU::Engineering::Chemical engineering::Biotechnology
Issue Date: 2012
Abstract: Biopolymeric hydrogels have been utilized as a technique to provide three-dimensional structures and microenvironment for many cell types in-vitro and in-vivo. Ca-alginate hydrogels have the potential of being a biocompatible polymeric scaffold with structurally similarity to the extra-cellular matrix. Recently in our lab, we have shown that it is able to support proliferation of encapsulated hematopoietic stem cells in-vitro. To better understand and control the impact of biophysical cues provided by alginate hydrogels, we performed mechanical and structural characterization of Ca-alginate hydrogels in varying chemical compositions. In this study, the effects of alginate viscosity, calcium ions and alginate concentration on the mechanical properties, surface topography, and swelling abilities were investigated.
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Student Reports (FYP/IA/PA/PI)

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