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https://hdl.handle.net/10356/50537
Title: | Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease | Authors: | Cher, Bernard Toh Hui | Keywords: | DRNTU::Science::Biological sciences | Issue Date: | 2011 | Source: | Cher, B. T. H. (2011). Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease. Doctoral thesis, Nanyang Technological University, Singapore. | Abstract: | Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mutation was a gross deletion where the CD18 gene was truncated and joined to the next gene on the chromosome, PTTG1IP. | URI: | https://hdl.handle.net/10356/50537 | DOI: | 10.32657/10356/50537 | Schools: | School of Biological Sciences | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SBS Theses |
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File | Description | Size | Format | |
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Bernard Cher Thesis Final.pdf | 4.31 MB | Adobe PDF | View/Open |
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