Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/50537
Title: Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
Authors: Cher, Bernard Toh Hui
Keywords: DRNTU::Science::Biological sciences
Issue Date: 2011
Source: Cher, B. T. H. (2011). Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease. Doctoral thesis, Nanyang Technological University, Singapore.
Abstract: Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mutation was a gross deletion where the CD18 gene was truncated and joined to the next gene on the chromosome, PTTG1IP.
URI: https://hdl.handle.net/10356/50537
DOI: 10.32657/10356/50537
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SBS Theses

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