Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/5280
Full metadata record
DC FieldValueLanguage
dc.contributor.authorFlorencia Edith Wiriaen
dc.date.accessioned2008-09-17T10:46:59Zen
dc.date.available2008-09-17T10:46:59Zen
dc.date.copyright2007en
dc.date.issued2007en
dc.identifier.citationFlorencia, E. W. (2007). Developing a novel biocomposite on selective laser sintering for tissue engineering. Doctoral thesis, Nanyang Technological University, Singapore.en
dc.identifier.urihttps://hdl.handle.net/10356/5280en
dc.description.abstractSelective Laser Sintering (SLS) is used to fabricate tissue engineering scaffold due to its versatility in processing various polymeric materials and good stability of its products. Propriety SLS materials are non-biocompatible as they were conventionally invented for production of industrial parts. Suitable biomaterial powders that can be processed in SLS without allowing damages on the material properties need to be identified. A theoretical study based on heat transfer phenomena during SLS process was carried out to identify the significant biomaterial and laser beam properties that influence the sintering result. Poly(vinyl alcohol) (PVA) and hydroxyapatite (HA) were identified as elements for the biocomposite. The most prominent sintering results were obtained by mechanical mixing of as-received PVA and HA powder, which yielded homogenous biocomposite powders with good repeatability. Characterization studies found that chemical composition of PVA as the scaffold matrix was not affected during the sintering process. PVA/HA (5 vol.% HA) scaffolds gave compression stress and compression modulus up to 2.26 MPa and 8.30 MPa, respectively, which is suitable for application in the craniomaxillofacial skeleton area. Cell culture study using osteoblast-like Saos-2 cells found that cell proliferation was favourable on the SLS fabricated scaffold.en
dc.rightsNanyang Technological Universityen
dc.subjectDRNTU::Engineering::Bioengineeringen
dc.titleDeveloping a novel biocomposite on selective laser sintering for tissue engineeringen
dc.typeThesisen
dc.contributor.supervisorChua Chee Kaien
dc.contributor.schoolSchool of Mechanical and Aerospace Engineeringen
dc.description.degreeDOCTOR OF PHILOSOPHY (MAE)en
dc.contributor.supervisor2Leong Kah Faien
dc.identifier.doi10.32657/10356/5280en
item.fulltextWith Fulltext-
item.grantfulltextopen-
Appears in Collections:MAE Theses
Files in This Item:
File Description SizeFormat 
MAE-THESES_1031.pdf14.37 MBAdobe PDFThumbnail
View/Open

Google ScholarTM

Check

Altmetric

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.