Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/5292
Title: DNA and protein sequence analysis
Authors: Yong, Kian Yan.
Keywords: DRNTU::Engineering::Mechanical engineering::Bio-mechatronics
Issue Date: 2007
Source: Yong, K. Y. (2007). DNA and protein sequence analysis. Master’s thesis, Nanyang Technological University, Singapore.
Abstract: The objective of this thesis is to improve the analysis of DNA and protein sequences. Sequence analysis is an important step in drug design to find the relationship among DNA sequences, protein sequences and their functions. The effectiveness of a drug is very much dependent on the correct associations of the sequences to their functions. In this thesis, three novel methods have been developed to enhance the analysis of DNA and protein sequences. Two of the methods target the alignment and prediction of motif sites in DNA sequences. Their improvements are made by introducing joint and vector weight matrix scoring scheme. The third method targets the protein secondary structures, by using new classification indices. The new results show that the structures can be classified into more categories as compared with the existing methods, which hydrophobicity factor is solely considered as a classification index.
URI: http://hdl.handle.net/10356/5292
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:MAE Theses

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