dc.contributor.authorWu, Min
dc.date.accessioned2013-05-30T07:16:30Z
dc.date.accessioned2017-07-23T08:29:46Z
dc.date.available2013-05-30T07:16:30Z
dc.date.available2017-07-23T08:29:46Z
dc.date.copyright2011en_US
dc.date.issued2011
dc.identifier.citationWu, M. (2011). Mining protein complexes from protein interaction data. Doctoral thesis, Nanyang Technological University, Singapore.
dc.identifier.urihttp://hdl.handle.net/10356/53200
dc.description.abstractProtein complexes play key roles in various important cellular processes, such as transcription, translation and so on. However, experimental detection of protein complexes is very time-consuming and tedious. That is why currently we still have only a limited number of known protein complexes. Therefore, computational methods are highly desired to generate high-quality candidates of protein complexes for wetlab validation. Meanwhile, protein complexes are analyzed to have substructures, i.e., a protein complex has several proteins to form a core and other proteins in periphery as attachments. Although there are already many computational methods for detecting protein complexes from PPI data, most of them fail to reveal this inherent organization of protein complexes.en_US
dc.format.extent149 p.en_US
dc.language.isoenen_US
dc.subjectDRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciencesen_US
dc.titleMining protein complexes from protein interaction dataen_US
dc.typeThesis
dc.contributor.schoolSchool of Computer Engineeringen_US
dc.contributor.supervisorLi Xiaoli
dc.contributor.supervisorKwoh Chee Keongen_US
dc.description.degreeDOCTOR OF PHILOSOPHY (SCE)en_US


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