Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/53442
Title: | Microfluidic chip development for medical application | Authors: | Chong, Zhi Wei. | Keywords: | DRNTU::Engineering::Manufacturing::Product design DRNTU::Engineering::Mechanical engineering::Fluid mechanics |
Issue Date: | 2013 | Abstract: | From inkjet printhead to micro-pneumatic systems, the field of microfluidics has been nothing short of a revolution. With advancements in the technology, micro-fluidics has also opened up a vast array of possibilities in biological applications. By utilizing the micro differences in the cell sizes and deformability of circulating tumor cells (CTCs) and normal blood cells, the complete operation from tumor cell capture to cell counting can now be done on a chip. This Final Year Project focuses on the fluid flow simulation of the Microsieve Lab-Chip Device in order to provide more insights into the design of the micro device prior to manufacturing and laboratory testing via the use of ANSYS Workbench. The study on the flow aims to establish a relation between the entry flow rates of the fluid into the micro device and the formation of dead volumes within the fluid chamber, which may interfere with tumor cell collection. Various designs of the chamber will also be looked into to determine the effect that geometrical design differences may have on the formations of dead volumes within the chamber. | URI: | http://hdl.handle.net/10356/53442 | Schools: | School of Mechanical and Aerospace Engineering | Organisations: | A*STAR Singapore Institute of Manufacturing Technology | Rights: | Nanyang Technological University | Fulltext Permission: | restricted | Fulltext Availability: | With Fulltext |
Appears in Collections: | MAE Student Reports (FYP/IA/PA/PI) |
Page view(s) 50
432
Updated on Mar 28, 2024
Download(s) 50
31
Updated on Mar 28, 2024
Google ScholarTM
Check
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.