Please use this identifier to cite or link to this item:
Title: The identification of cis-regulatory elements of runx3
Authors: Nah, Giselle Sek Suan
Keywords: DRNTU::Science::Biological sciences
Issue Date: 2012
Abstract: The RUNX3 gene is essential for the development of multiple cell lineages and is frequently involved in a variety of cancers and immunological diseases. Despite such frequent association with human diseases, the transcriptional regulation of Runx3 remains elusive. Owing to the huge ~350 kb Runx3 locus and complexity of the use of two alternate promoters for transcription, the search for regulatory regions outside the immediate promoters by traditional methods such as DNase I hypersensitive assay, proved to be a daunting task.
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SBS Theses

Files in This Item:
File Description SizeFormat 
  Restricted Access
16.89 MBAdobe PDFView/Open

Page view(s) 10

checked on Oct 20, 2020

Download(s) 10

checked on Oct 20, 2020

Google ScholarTM


Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.