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Title: Hemodynamics in the cerebral circulation : numerical studies and experimental investigation
Authors: Chen, Liang
Keywords: DRNTU::Engineering::Mechanical engineering::Surgical assistive technology
Issue Date: 2005
Source: Chen, L. (2005). Hemodynamics in the cerebral circulation : numerical studies and experimental investigation. Doctoral thesis, Nanyang Technological University, Singapore.
Abstract: A nonlinear one-dimensional numerical model has been built up to study the cerebral blood flow in the circle of Willis (CoW). Three friction terms and two tube laws have been compared. A clinical-static autoregulation model obtained from the literature has been applied in the numerical model. Then the numerical model has been used to simulate hemodynamic changes in the CoW before and after clamping of internal carotid arteries (ICA) during carotid endarterectomy. The results show that the numerical model is a possible clinical tool in the estimation of hemodynamics in the patients. The interactive role of communicating arteries has also been studied. The results show that the diameters of anterior communicating artery and posterior communicating arteries together with the degree of stenoses of ICAs highly influence the cerebral hemodynamics.
DOI: 10.32657/10356/5378
Rights: Nanyang Technological University
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Theses

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