Modelling and control of epileptic seizures

Abstract

As per the report of World Health Organization, three out of one thousand people in the

world have epilepsy and in 30% of such patients uncontrolled seizures prevail even after

pharmacological epileptic therapy using Anti Epileptic Drugs. As these patients live in a

constant fear ofhaving seizure at any time, some of them undergo surgical epilepsy treatment

in which the seizure onset zone is indentified clinically by neurosurgeons and is resected. The

clinical determination of seizure onset zone of the cortex is carried out after meticulously

analysing the electroencephalogram and/or electrocorticogram data of the patient, which is

recorded for a week or longer unless enough number of seizures are captured. This requires

long hospitalization time, sometimes with invasive electrodes placed in the patient's cortex.