Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/6018
Title: Effect of plant extract on the preservation of organ/tissue : an investigation on cell viability and mechanical properties
Authors: Bai, Lin
Keywords: DRNTU::Engineering::Bioengineering
Issue Date: 2005
Abstract: In this study, Aloe Vera extract has been explored as a pharmacologic additive in tissue preservation medium to prolong the “safe” ischemia time. Aortic (AV) and pulmonary (PV) valve leaflets were harvested from freshly procured porcine hearts and then subjected to preservation treatment of different Aloe Vera extract concentrations and ischemic time of 0, 18, and 60 hours. Uniaxial mechanical test and MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) assay were performed to assess the mechanical properties and cell viability, respectively. The result showed that the preservation time (P<0.05) has a significant effect on the Failure Strain of AV and the Failure Load of PV, as well as the OD of PV.
URI: http://hdl.handle.net/10356/6018
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:MAE Theses

Files in This Item:
File Description SizeFormat 
MAE-THESES_51.pdf
  Restricted Access
2.39 MBAdobe PDFView/Open

Page view(s)

297
checked on Sep 30, 2020

Download(s)

13
checked on Sep 30, 2020

Google ScholarTM

Check

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.