Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/61090
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dc.contributor.authorLi, Yihan
dc.date.accessioned2014-06-04T08:15:13Z
dc.date.available2014-06-04T08:15:13Z
dc.date.copyright2014en_US
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/10356/61090
dc.description.abstractIt is well known that ultraviolet ray (UVR) irradiation can cause cutaneous damage, hence dermatologists encourage people to use sunscreen to absorb or reflect a number of the sun's UV radiation on the skin exposed to sunlight. In recent years, sunscreen is extensively used in our daily life to protect the damage to our skin by the sun. Among the complex components in sunblock, Titanium Dioxide (TiO2) is an important one due to its ultraviolet ray filterable ability. For the purpose of improving the performance of sun cream products, the popularity of replacing nano-sized titanium dioxide particles with normal TiO2 has increased rapidly, however, like many other technologies, nanotechnology offers both pros and potential cons, scientists have found that due to the nanoparticles’ (NPs’) enhanced physicochemical property, NPs are more active, thus they have greater opportunity to interact with cells and lead to certain cytotoxicity, may potentially damage skin and even able to diffuse into circulation system to induce skin cancer. One believed way to minimize the potential side effects is to wash TiO2 NPs away from skin at the end of the day. However, the effectiveness of this strategy hasn’t been evaluated, which might be due to the lack of a user-friendly and convenient technology for skin analysis. Here, we show for the first time that the portable Raman microscope can reveal and quantify the residue of TiO2 NPs on the skin after cleaning. By taking porcine skin as the example, we prove that cleaning with detergent is the quickest and most efficient way to remove TiO2 NPs from the skin.en_US
dc.format.extent47 p.en_US
dc.language.isoenen_US
dc.subjectDRNTU::Engineeringen_US
dc.titleDiagnosis of sunscreen residue on skin with portable Raman microscopeen_US
dc.typeThesis
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.description.degree​Master of Science (Biomedical Engineering)en_US
dc.contributor.supervisor2Xu, Chenjieen_US
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