Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/61644
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dc.contributor.authorChee, Medaleine Jee Iue
dc.date.accessioned2014-07-01T07:13:41Z
dc.date.available2014-07-01T07:13:41Z
dc.date.copyright2014en_US
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/10356/61644
dc.description.abstractTheranostic probes play an important role on the bioimaging and sensing platform to provide diagnostics and therapeutics application. The development of theranostic agent can combine both diagnostics and therapeutics that aids in the process of Photodynamic Therapy (PDT) by allowing the imaging of the disease model. This water soluble photosensitizer that has been frequently used in photothermal therapy, is conjugated with gold nanorods to form a theranostic agent. The known properties of this photosensitizer producing reactive oxygen species (ROS) upon appropriate light irradiation is the key component of PDT that aids in the destruction of cancerous cells. In this project, we have conjugated both the water soluble photosensitizer and gold nanorods to develop the theranostic agent. We characterized the conjugation of this probe and conducted PDT to determine the generation of ROS. Preliminary phantom studies have also been conducted where results shown enhancement in the conjugated probe that was brought about by the combination of adherence of the photosensitizer and surface plasmon resonance of gold nanorods.en_US
dc.format.extent48 p.en_US
dc.language.isoenen_US
dc.rightsNanyang Technological University
dc.subjectDRNTU::Engineering::Bioengineeringen_US
dc.titlePhotosensitizer conjugated gold nanorods for photoacoustic imagingen_US
dc.typeFinal Year Project (FYP)en_US
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.description.degreeBachelor of Engineering (Chemical and Biomolecular Engineering)en_US
dc.contributor.supervisor2Liu Quanen_US
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Appears in Collections:SCBE Student Reports (FYP/IA/PA/PI)
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