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Title: The biosynthesis of vitamin E in the bacteria escherichia coli
Authors: Lieviant, Jane Andrea
Keywords: DRNTU::Science::Biological sciences::Molecular biology
Issue Date: 2014
Abstract: The lipid antioxidant vitamin E is among the supplements essential for humans and animals. Its biosynthesis pathways in plants and cyanobacteria have been elucidated and studied, cloned and expressed in order to enhance the vitamin E contents of producer crops. For decades, Escherichia coli has been the primary workhorse for recombinant pharmaceuticals, especially for small molecules and proteins not requiring complex post-translational modifications. This work reviews the biosynthesis of tocochromanols, their functions, and past efforts in engineering the pathway, and the possibilities for E. coli as the optimal host system.
Schools: School of Chemical and Biomedical Engineering 
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Theses

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