Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/63139
Title: Isolation of cancer cell using an integrated magnetofluidic device for magnetic cell isolation
Authors: Wong, Qi Ying
Keywords: DRNTU::Science::Physics::Electricity and magnetism
Issue Date: 2015
Abstract: Microfabrication technologies have been advancing over the years and have proved to be an influence especially in the biological sciences. With the integration of a microstripline together with a microfluidic channel, magnetofluidic chips are made. In this project, techniques such as photolithography, ion-milling, electron beam evaporation and oxygen plasma bonding are used in the fabrication of the device. The integrated magnetofluidic device utilizes two types of physics, fluid dynamics and electromagnetism. In this project, two types of microstripline, single and double microstriplines were modelled on COMSOL Multiphysics and their magnetic and joule heating properties were analysed. In the analysis of the microstripline structures, it allow for the calculation of the magnetic force through the generated magnetic field. Flow rates were also modelled to achieve hydrodynamic focusing as it is important for attaining higher sorting efficiency. This was also done experimentally to demonstrate sorting of microparticles and magnetically tagged HeLa cancer cells. The integrated device can potentially be used for many bio-applications such as blood cleansing and cell separation.
URI: http://hdl.handle.net/10356/63139
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Student Reports (FYP/IA/PA/PI)

Files in This Item:
File Description SizeFormat 
WongQiYing_U1140743J.pdf
  Restricted Access
FYP Thesis6.03 MBAdobe PDFView/Open

Page view(s)

196
Updated on Jan 18, 2021

Download(s)

33
Updated on Jan 18, 2021

Google ScholarTM

Check

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.