dc.contributor.authorCao, Yuan
dc.date.accessioned2015-09-07T05:26:54Z
dc.date.accessioned2017-07-23T08:42:57Z
dc.date.available2015-09-07T05:26:54Z
dc.date.available2017-07-23T08:42:57Z
dc.date.copyright2015en_US
dc.date.issued2015
dc.identifier.citationCao, Y. (2015). Development of chemical and enzymatic peptide ligation strategies. Doctoral thesis, Nanyang Technological University, Singapore.
dc.identifier.urihttp://hdl.handle.net/10356/65380
dc.description.abstractProteins carry out virtually all the functions in almost every aspect of living organisms. To elucidate their roles in biological process, easy and convenient access to the proteins of interest is necessary. Chemical peptide synthesis and DNA-based recombinant technologies are the two major direct accesses to peptides/proteins. However, they have intrinsic limitations. Chemical synthesis has size limitation and DNA-based recombinant technology could not afford proteins with site-specific modifications. Peptide ligation strategies which enable the combined use of the above two would greatly expand the application scope. In my Ph.D research work, I mainly devoted to the development of peptide ligation strategies in both chemical and enzymatic manners.en_US
dc.format.extent150 p.en_US
dc.language.isoenen_US
dc.subjectDRNTU::Science::Biological sciences::Biochemistryen_US
dc.titleDevelopment of chemical and enzymatic peptide ligation strategiesen_US
dc.typeThesis
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.contributor.supervisorLiu Chuan Faen_US
dc.description.degreeDOCTOR OF PHILOSOPHY (SBS)en_US


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