Please use this identifier to cite or link to this item:
|Title:||Preparation of chiral EC(sp3)E’ phosphine-based mono- and di-nuclear palladium pincer complexes||Authors:||Tay, Wee Shan||Keywords:||DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds||Issue Date:||2016||Abstract:||Ten enantiopure Pd pincer complexes with aliphatic and unsymmetrical characteristics have been synthesized efficiently. Chirality on the ligand backbone was introduced via an asymmetric H-P bond addition reaction by two structurally-dissimilar catalysts with >99% ee’s. Challenging C(sp3)-H bond activation during palladation proceeded with high yields and excellent diastereoselectivities under optimized conditions. Several crystal structures were isolated and discussed. Selected pincer complexes were also employed in a chirality “self-breeding” protocol, in which infinite replicates of a catalyst may be synthesized by itself. Excellent results were obtained, with the selected complex being capable of producing itself with the exact absolute stereoconfiguration with >99% ee at RT.||URI:||http://hdl.handle.net/10356/67020||Fulltext Permission:||restricted||Fulltext Availability:||With Fulltext|
|Appears in Collections:||SPMS Theses|
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.