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Title: Synthesis of high value chemicals from biomass platform chemicals
Authors: Koh, Jackson Peng Fei
Keywords: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
Issue Date: 2016
Source: Koh, J. P. F. (2016). Synthesis of high value chemicals from biomass platform chemicals. Doctoral thesis, Nanyang Technological University, Singapore.
Abstract: In this thesis, the conversion of biomass to several high value chemicals via versatile and synthetically useful platform chemicals was described. These high value chemicals include a common intermediate that allow access to several potent NK1 receptor antagonists which are associated with the treatment of anxiety and emesis, as well as biologically active natural products aspergillides A and B with cytotoxic activity against mouse lymphocytic leukemia cell (L1210). In particular, the syntheses of aspergillides A and B was achieved such that all of the carbons present are derived from biomass derived platform chemicals. These demonstrate the feasibility of constructing valuable biologically active compounds using a sustainable chemical feedstock like biomass.
DOI: 10.32657/10356/67322
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Theses

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