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Title: Production of Nipah Virus VLPs
Authors: Ng, Say Yong
Keywords: DRNTU::Science::Biological sciences::Microbiology::Virology
Issue Date: 2016
Abstract: The Nipah Virus (NiV) is an emerging infectious virus that has caused outbreaks since 1998. It is a dangerous zoonotic virus with a 40-75% case fatality rate and the route of transmission is skewed towards human-to-human transmission in recent year. With no treatment available and only one vaccine that is licensed for horses, this necessitates the new treatments and vaccine urgently. Classified as a BSL4 virus, the research that can be done on it will hampers the development of new therapeutics. In this study we managed to culture and isolation Nipah virus-like particles in a BSL2 laboratory. This Nipah VLPs has the viral glycoproteins as an authentic virus but without any genetic material and is a potential vaccine.
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SBS Student Reports (FYP/IA/PA/PI)

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