Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/72510
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAng, Jing Yu-
dc.date.accessioned2017-08-17T02:08:45Z-
dc.date.available2017-08-17T02:08:45Z-
dc.date.issued2017-
dc.identifier.urihttp://hdl.handle.net/10356/72510-
dc.description.abstractNosocomial pathogens such as Pseudomonas aeruginosa form biofilms to thrive under stress conditions. Biofilm is a community of microorganisms where cells live close to each other and are encased in a protective layer of extracellular polymeric substances against host defenses and antibiotics. Living in the ‘post-antibiotic era’, many pathologists face issues with drug resistance. Herbal phytochemicals have been shown to exhibit anti-bacteria properties towards pathogenic bacteria. Hence, granule and raw herb form of several herb species (Coptis chinensis, Cortex phellodendri, Scutellaria baicalensis, Salvia miltiorrhiza and Rhizoma zingiberis) were extracted by different solvents and screened for the capacities to reduce growth, quorum sensing (QS) and biofilm formation. Raw Rhizoma zingiberis, Salvia miltiorrhiza, Scutellaria baicalensis, Coptis chinensis and Cortex phellodendri demonstrated capacities in reducing growth and QS at various concentrations: such as 33.3, 50, 100, 100, 50μg/ml. Granule Rhizoma zingiberis, Scutellaria baicalensis and Cortex phellodendri demonstrated capacities in reducing growth at various concentrations: such as 66.7, 100, 66.7μg/ml. Granule Rhizoma zingiberis, Scutellaria baicalensis and Cortex phellodendri demonstrated capacities in reducing QS at various concentrations: such as 16.7, 100, 66.7μg/ml. Raw Rhizoma zingiberis, Salvia miltiorrhiza and granule forms of Rhizoma zingiberis, Salvia miltiorrhiza and Cortex phellodendri demonstrated capacities in reducing biofilm formation at various concentrations: such as 2.1, 50, 4.2, 6.25, 66.7μg/ml. These phenotypic traits of each herb from this study provide guidance towards future studies.en_US
dc.format.extent45 p.en_US
dc.language.isoenen_US
dc.rightsNanyang Technological University-
dc.subjectDRNTU::Science::Biological sciences::Microbiologyen_US
dc.titleInfluence of five Chinese herbs on bacterial growth, quorum sensing and biofilm formationen_US
dc.typeFinal Year Project (FYP)en_US
dc.contributor.supervisorZhao Yanen_US
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.description.degreeBachelor of Science in Biomedical Sciencesen_US
dc.contributor.organizationSingapore Centre for Environmental Life Sciences Engineeringen_US
dc.contributor.supervisor2Yang Liangen_US
item.fulltextWith Fulltext-
item.grantfulltextrestricted-
Appears in Collections:SBS Student Reports (FYP/IA/PA/PI)
Files in This Item:
File Description SizeFormat 
Thesis Ang Jing Yu AY2017 S1.pdf
  Restricted Access
3.01 MBAdobe PDFView/Open

Google ScholarTM

Check

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.