Synergy of novel cationic polymer with antibiotics in pseudomonas aeruginosa

Abstract

This study attempts to replicate and quantify the interaction between a novel polymer, 70-5, synthesized by SCBE (School of Chemical and Biochemical Engineering) and antibiotics of several different classes against Pseudomonas aeruginosa. We have been able to replicate beneficial effects at several concentrations of polymer for some rifampicin, trimethoprim and chloramphenicol but not ciprofloxacin. Additionally, in this study the data was insufficient to establish a trend in dose vs activity.