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Title: Programming of an Arduino control unit for Cell Culture Incubation Chamber
Authors: Lim, Ding Yan
Keywords: DRNTU::Engineering::Bioengineering
Issue Date: 2018
Abstract: Today, the problems faced by researchers include the cost associated with recalls of drugs which have side effects went undetected and lacked effective and low-cost model systems to analyse them further. Three-dimensional (3D) tissue models offer more effective and robust pre-clinical screening as compared to two-dimensional (2D) tissue models which are relatively lower in cost and shorter time to cultivate. Devices currently available on the market are not able to handle drug perfusion at cell-viable conditions for long-term testing and imaging experiments at a lower cost. This paper suggests building a portable microcontroller to integrate with portable incubator enclosure for cell experiments and drug screening of three-dimensional (3D) tissue models, presenting a useful diagnostic tool for screening cost-effectively. The portable microcontroller must be able to regulate consistent environment for cell experiments to perform long-term testing and imaging without any disruption to cell viability.
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Student Reports (FYP/IA/PA/PI)

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