Programming of an Arduino control unit for Cell Culture Incubation Chamber

Abstract

Today, the problems faced by researchers include the cost associated with recalls of drugs which have side effects went undetected and lacked effective and low-cost model systems to analyse them further. Three-dimensional (3D) tissue models offer more effective and robust pre-clinical screening as compared to two-dimensional (2D) tissue models which are relatively lower in cost and shorter time to cultivate. Devices currently available on the market are not able to handle drug perfusion at cell-viable conditions for long-term testing and imaging experiments at a lower cost. This paper suggests building a portable microcontroller to integrate with portable incubator enclosure for cell experiments and drug screening of three-dimensional (3D) tissue models, presenting a useful diagnostic tool for screening cost-effectively. The portable microcontroller must be able to regulate consistent environment for cell experiments to perform long-term testing and imaging without any disruption to cell viability.