Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/76751
Title: 3D bioprinting of artificial skin substrates
Authors: Neo, Richmond Yu Wei
Keywords: DRNTU::Engineering::Materials
Issue Date: 2019
Abstract: In recent years, there has been intensive research to develop skin substitutes to replace the current method of tissue grafting from donor sites. Various tissue-engineered skin replacements have been developed which are currently available on the market. However, these skin replacements do not represent a true, fully functional skin replacement as they each have their own unique drawbacks. This study aims to develop a fully functional skin model to mimic real skin tissue as close as possible. This is done by coating a bio-printed hydrogel scaffold with a recombinant protein which will facilitate cell migration, adhesion and proliferation. The Human Dermal Fibroblast (HDF) cells seeded onto the scaffold were incubated for up to 14 days and the viability of the cells were characterised via Live/Dead cell staining. Images of the cells was taken at days 1, 3, 7 and 14 using a microscope. The images depicted positive cell adhesion and proliferation. A dry sample of the bio-printed hydrogel scaffold was also characterised using Scanning Electron Microscopy to analyse the pore morphology, size and density.
URI: http://hdl.handle.net/10356/76751
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:MSE Student Reports (FYP/IA/PA/PI)

Files in This Item:
File Description SizeFormat 
FYP Report_RichmondNeoYuWei.pdf
  Restricted Access
FYP Report_RichmondNeo1.73 MBAdobe PDFView/Open

Page view(s)

173
Updated on Jul 27, 2021

Download(s) 50

18
Updated on Jul 27, 2021

Google ScholarTM

Check

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.