Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/78746
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dc.contributor.authorChan, Darren Chun Kit
dc.date.accessioned2019-06-26T07:09:22Z
dc.date.available2019-06-26T07:09:22Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/10356/78746
dc.description.abstractSodium Dodecylsulfate (SDS) is a widely used surfactant known for its effectiveness in decellularization. In this report, utilising Quantitative Phase Imaging (QPI) methods to observe changes within L929 fibroblast cells to quantify the steps from adding surfactant to cell detachment. The objective is to observe the behaviour of cells from introduction of SDS leading to cell detachment. Changes in shape, size, height and even volume can be quantified by QPI. The study and tests showed that SDS in all cases detaches the cell and removes all cell materials from surface. The process begins with bloating of the cell followed by bursting due to SDS action on cell membranes. The experiments show that SDS is an ideal surfactant for removing cells completely and in this report are the results of the investigation on the actions and steps leading up to cell detachment.en_US
dc.format.extent32 p.en_US
dc.language.isoenen_US
dc.rightsNanyang Technological University
dc.subjectEngineering::Mechanical engineeringen_US
dc.titleInvestigation of the effect of sodium dodecylsulfate (SDS) on cell-detachment using quantitative phase interferometry (QPI) methoden_US
dc.typeFinal Year Project (FYP)en_US
dc.contributor.supervisorChian Kerm Sin, Sandyen_US
dc.contributor.schoolSchool of Mechanical and Aerospace Engineeringen_US
dc.description.degreeBachelor of Engineering (Mechanical Engineering)en_US
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Appears in Collections:MAE Student Reports (FYP/IA/PA/PI)
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