Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/78854
Title: Bioprospecting of medicinal plants showing antibacterial activity against Pseudomonas aeruginosa
Authors: Lim, Vernice Wen Min
Keywords: Science::Biological sciences::Microbiology::Bacteria
Science::Biological sciences::Botany::Plant physiology
Issue Date: 2019
Abstract: The pressure exerted by the rising threat of antimicrobial resistance has forced a flurry of scientific investigations to synthesise more effective antibiotics to counter the highly resistant pathogens, but to no avail. Scientists now set their sights on alternative sources, especially plants for they have been utilised for medical purposes in thousand-year-old traditional medicine. However, the molecular basis of antibacterial properties of plant extracts is largely unknown. Therefore in this study, we aim to evaluate the antibacterial activity of local herbal plants against both the planktonic cells and biofilms of Pseudomonas aeruginosa PAO1 Wild-Type strain through microtiter plate assays. Six out of 159 plant extracts (3.77%) inhibited P. aeruginosa growth. While Hydrocotyle verticillata, Citrus hybrid, Sphaeropteris lepifera (Hook.) Tyron, Pedilanthus tithymaloides, and Ficus microcarpa showed potent antibacterial activity against the bacteria, only Citrus grandis (L.) Osbeck expressed inhibitory effects on biofilms. These results suggest that plants are a viable source of antimicrobials, and thus merit further studies.
URI: http://hdl.handle.net/10356/78854
Rights: Nanyang Technological University
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SBS Student Reports (FYP/IA/PA/PI)

Files in This Item:
File Description SizeFormat 
Thesis FINAL.pdf
  Restricted Access
1.65 MBAdobe PDFView/Open

Page view(s)

175
Updated on Jun 23, 2021

Download(s) 50

21
Updated on Jun 23, 2021

Google ScholarTM

Check

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.