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Title: Gastric-floating microcapsules provide controlled and sustained release of multiple cardiovascular drugs
Authors: Lee, Wei Li
Wee, Peixin
Nugraha, Chandra
Loo, Say Chye Joachim
Keywords: DRNTU::Engineering::Materials::Biomaterials
Issue Date: 2013
Source: Lee, W. L., Wee, P., Nugraha, C., & Loo, S. C. J. (2013). Gastric-floating microcapsules provide controlled and sustained release of multiple cardiovascular drugs. Journal of Materials Chemistry B, 1(8), 1090-1095.
Series/Report no.: Journal of materials chemistry B
Abstract: Floating polymeric microcapsules that simultaneously entrap multiple drugs were prepared using a solid/water/oil/water emulsion solvent evaporation method, based on harnessing interfacial phenomena and manipulation of the solvent removal process. The fabricated microcapsules exhibited excellent buoyancy in simulated gastric fluid and provided controlled and sustained release of multiple drugs for up to 24 h, thus revealing their potential as a rate-controlled oral drug delivery system.
DOI: 10.1039/c2tb00495j
Schools: School of Materials Science & Engineering 
Rights: © 2013 Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MSE Journal Articles

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