Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/79354
Title: Biomass derived furfural-based facile synthesis of protected (2S)-phenyl-3-piperidone, a common intermediate for many drugs
Authors: Koh, P.-F.
Wang, P.
Huang, J.-M.
Loh, T.-P.
Keywords: DRNTU::Science::Chemistry
Issue Date: 2014
Source: Koh, P.-F., Wang, P., Huang, J.-M., & Loh, T.-P. (2014). Biomass derived furfural-based facile synthesis of protected (2S)-phenyl-3-piperidone, a common intermediate for many drugs. Chemical communications, 50(61), 8324-8327.
Series/Report no.: Chemical communications
Abstract: An efficient synthetic route towards tosyl-protected (2S)-phenyl-3-piperidone, a common intermediate for many drugs, has been developed in 5 steps in 54% yield from biomass derived furfural. The synthetic utility of the piperidone core structure was demonstrated with the synthesis of a NK1 receptor antagonist.
URI: https://hdl.handle.net/10356/79354
http://hdl.handle.net/10220/25021
ISSN: 1359-7345
DOI: 10.1039/C4CC02645D
Rights: © 2014 The Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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