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Title: Label-free, electrochemical detection of methicillin-resistant staphylococcus aureus DNA with reduced graphene oxide-modified electrodes
Authors: Wang, Zhijuan
Zhang, Juan
Chen, Peng
Zhou, Xiaozhu
Yang, Yanli
Wu, Shixin
Han, Yu
Wang, Lianhui
Chen, Peng
Boey, Freddy Yin Chiang
Niu, Li
Zhang, Qichun
Bo, Liedberg
Zhang, Hua
Keywords: DRNTU::Science::Medicine::Biosensors
Issue Date: 2011
Source: Wang, Z., Zhang, J., Chen, P., Zhou, X., Yang, Y., Wu, S., Niu, L., Han, Y., Wang, L., Chen, P., Boey, F., Zhang, Q., Liedberg, B., & Zhang, H. (2011). Label-free, Electrochemical Detection of Methicillin-Resistant Staphylococcus Aureus DNA with Reduced Graphene Oxide-Modified Electrodes. Biosensors and Bioelectronics, 26(9), 3881–3886.
Series/Report no.: Biosensors and Bioelectronics
Abstract: Reduced graphene oxide (rGO)-modified glassy carbon electrode is used to detect the methicillinresistant Staphylococcus aureus (MRSA) DNA by using electrochemical impedance spectroscopy. Our experiments confirm that ssDNA, before and after hybridization with target DNA, are successfully anchored on the rGO surface. After the probe DNA, pre-adsorbed on rGO electrode, hybridizes with target DNA, the measured impedance increases dramatically. It provides a new method to detect DNA with high sensitivity (10−13 M, i.e., 100 fM) and selectivity.
DOI: 10.1016/j.bios.2011.03.002
Schools: School of Materials Science & Engineering 
Rights: © 2011 Elsevier B.V. This is the author created version of a work that has been peer reviewed and accepted for publication by Biosensors and Bioelectronics, Elsevier. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MSE Journal Articles

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