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Title: Design and synthesis of multivalent neoglycoconjugates by click conjugations
Authors: Ding, Feiqing
Ji, Li
William, Ronny
Chai, Hua
Liu, Xue-Wei
Keywords: DRNTU::Science::Chemistry::Inorganic chemistry
Issue Date: 2014
Source: Ding, F., Ji, L., William, R., Chai, H., & Liu, X.-W. (2014). Design and synthesis of multivalent neoglycoconjugates by click conjugations. Beilstein Journal of Organic Chemistry, 10, 1325-1332.
Series/Report no.: Beilstein journal of organic chemistry
Abstract: A highly stereoselective BF3∙OEt2-promoted tandem hydroamination/glycosylation on glycal scaffolds has been developed to form propargyl 3-tosylamino-2,3-dideoxysugars in a one-pot manner. Subsequent construction of multivalent 3-tosylamino-2,3-dideoxyneoglycoconjugates with potential biochemical applications was presented herein involving click conjugations as the key reaction step. The copper-catalyzed regioselective click reaction was tremendously accelerated with assistance of microwave irradiation.
ISSN: 1860-5397
DOI: 10.3762/bjoc.10.134
Schools: School of Physical and Mathematical Sciences 
Rights: © 2014 Ding et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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