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Title: Emerging Designs of Activatable Photoacoustic Probes for Molecular Imaging
Authors: Miao, Qingqing
Pu, Kanyi
Keywords: Activatable probe
Photoacoustic imaging
Issue Date: 2016
Source: Miao, Q., & Pu, K. (2016). Emerging Designs of Activatable Photoacoustic Probes for Molecular Imaging. Bioconjugate Chemistry, 27(12), 2808–2823.
Series/Report no.: Bioconjugate Chemistry
Abstract: Photoacoustic (PA) imaging as a new hybrid imaging modality holds great promise for real-time in vivo monitoring of biological processes with deep tissue penetration and high spatial resolution. To endow PA imaging with the ability to provide real-time molecular information at disease sites, molecular probes that can change their PA signals responding to the target or event of interest have to be developed. This review focuses on the recent development of smart activatable PA probes for molecular imaging. A brief summary of PA imaging agents is given first, followed by the detailed discussion of the contemporary design approaches toward activatable PA probes for different imaging applications. At last, the current challenges are highlighted.
ISSN: 1043-1802
DOI: 10.1021/acs.bioconjchem.6b00641
Schools: School of Chemical and Biomedical Engineering 
Rights: © 2016 American Chemical Society. This is the author created version of a work that has been peer reviewed and accepted for publication by Bioconjugate Chemistry, American Chemical Society. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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