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Title: Micro-optical coherence tomography tracking of magnetic gene transfection via Au–Fe3O4 dumbbell nanoparticles
Authors: Shi, Wei
Liu, Xinyu
Wei, Chao
Xu, Zhichuan J.
Sim, Stanley Siong Wei
Liu, Linbo
Xu, Chenjie
Keywords: Heterogeneous nanoparticles
Gene delivery
Dumbbell nanoparticles
Micro-optical coherence tomography
Issue Date: 2015
Source: Shi, W., Liu, X., Wei, C., Xu, Z. J., Sim, S. S. W., Liu, L., et al. (2015). Micro-optical coherence tomography tracking of magnetic gene transfection via Au–Fe3O4 dumbbell nanoparticles. Nanoscale, 7(41), 17249-17253.
Series/Report no.: Nanoscale
Abstract: Heterogeneous Au-Fe3O4 dumbbell nanoparticles (NPs) are composed of Au NPs and Fe3O4 NPs that bring in optical and magnetic properties respectively. This article reports the engineering of Au-Fe3O4 NPs as gene carriers for magnetic gene transfection as well as contrast agents for micro-optical coherence tomography (μOCT). As a proof-of-concept, Au-Fe3O4 NPs are used to deliver the green fluorescent protein to HEK 293T cells and their entrance into the cells is monitored through μOCT.
ISSN: 2040-3364
DOI: 10.1039/C5NR05459A
Schools: School of Chemical and Biomedical Engineering 
School of Electrical and Electronic Engineering 
School of Materials Science & Engineering 
Rights: © 2016 Royal Society of Chemistry. This is the author created version of a work that has been peer reviewed and accepted for publication by Nanoscale, Royal Society of Chemistry. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:EEE Journal Articles
MSE Journal Articles
SCBE Journal Articles

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